ชานนธ์ ตลอดไธสง และ ศิรินันท์ กุลชาติ*
Self-healing materials promise new technologies that can imitate the mechanisms of self-healing in natural organisms. Scientists are developing these concepts to improve the lifetime of materials, leading to reduced cost (both financial and environmental) of maintenance or re-purchase. Generally, self-healing materials are polymers with dynamic properties at both the molecular level and supramolecular level, termed Constitutional Dynamic Chemistry. Provided that materials have been damaged, self-repair occurs via the reversible reactions embedded in the material. Self-repair can proceed automatically or be triggered by external stimuli such as heat, light, pressure, acid or base. Recently, researchers have applied these materials towards applications in the biomedical field, sensing, new materials, pharmaceuticals, and tissue engineering. In this article, we will focus on the mechanisms of self-healing in these materials and their applications.
At low temperatures and strong magnetic fields, the Hall resistance increases stepwise with magnetic field. Its value at each step is h/ne2, where n is an integer. The integer quantum Hall effect can be understood on a basis of the number of electrons occupying the extended states and the localized states. The integer n is interpreted as a topological invariance, Chern number.
พัชระ นาเสงี่ยม และ คำรณ สุนัติ*
As the complexity of optimization problems have increased over the last few decades, such as the benchmark functions established by the Congress on Evolutionary Computation-2017 (CEC-2017), the development of new optimization techniques has become evident more than previously. Modern algorithms are required because conventional algorithms are inadequate to solve complicated problems. The Nearest Neighbor Cuckoo Search (NNCS), with probabilistic mutation, is studied in this work. It is the improved cuckoo search algorithm using the topology of the nearest-neighbor population and probabilistic mutation to fix the step-size problem in a search space. The proposed algorithm can solve this problem without using any NN topology, and it provides a better result than the NNCS. The of 0.06 was selected for both low and high dimensional problems. The proposed method has been compared with other previously-reported algorithms such as ABC, CS, PSO, FA, GSA, GWO, MVO, MFO, QPSO, LCA, NNCS in order to investigate the improvement of efficiency over the original CS.
ภาษกรณ์ ธีรพงศ์ไพศาล จรัสลักษณ์ เพชรวัง ศรัณยู ใคลคลาย และ ปรินุช ชุมแก้ว*
Chemical investigation on the stems of A. cucullata led to the isolation of one aporphine alkaloid, 6a,7-didehydrobulbocapnine methyl ether (1) and two protoberberine alkaloids, 9-demethyloxypalmatine (2), and 8,13-dioxo-14-hydroxytetrahydropalmatine (3). Their structures were characterized by mainly 1H and 13C NMR spectral data and compared with previously reported. Compounds 1-3 were also evaluated for antimicrobial activities against Staphylococcus aureus (ATCC25923), Bacillus subtilis (ATCC6633), Methicillin-resistant Staphylococcus aureus (SK1), Pseudomonas aeruginosa (ATCC27853) and Escherichia coli (ATCC25922) by broth micro dilution method. Compound 2 was found to be the most active compound, while compound 3 was the least active. The lowest minimum inhibitory concentration (MIC) values of compound 2 were 25.0 µg/mL on S. aureus (ATCC25923) and B. subtilis (ATCC6633), and 50.0 µg/mL on Methicillin-resistant Staphylococcus aureus (SK1).
This study aims to examine the comparison of latent fingerprint development on the adhesive side of tapes by using various types of gentian violet. Four different adhesive tapes included crepe paper tape, duct tape, transparent tape and carton sealing tape, tested with three different commercial gentian violet type (a), type (b) and type (c). The latent fingerprint development was examined by the fingerprint experts through the Automated Fingerprint Identification System (AFIS). The average number of minutiae was then determined by using a two-way ANOVA at a significance level of 0.05. The results of the study showed that the average number of minutiae between gentian violet type (a) and (c) was different with a significance level of 0.05, while type (b) was not different at a significance level of 0.05. For the different types of tapes, the average number of minutiae between crepe paper tape and carton sealing tape was different with a significance level of 0.05. The average number of minutiae on carton sealing tape was higher than crepe paper tape whereas there were no differences with a significance level of 0.05 on duct tape and transparent tape.
วิศนีย์ ยิ่งประเสริฐ* และ เฉลิมพงศ์ บกสกุล
In this study, the effect of boric acid addition (5%, 10% and 15% w/w of solid content of resin) into urea formaldehyde resin (UF) on resin properties was evaluated. Shear strength, formaldehyde emission content, white rot (Trametes versicolor) and brown rot (Gloeophyllum striatum) resistance and subterranean termite (Coptotermes gestroi) resistance of rubberwood plywood which was produced with UF resin added boric acid in certain amount were also investigated. It revealed that the addition of boric acid into UF resin help decrease pH of resin to acid condition. It caused the decreasing gel time and increasing solid content of UF resin. Formaldehyde emission content of rubberwood plywood produced with UF resin added boric acid was decreased. Boric acid addition into UF resin enhanced white rot and brown rot resistance. Subterranean termite resistance of rubberwood plywood produced with UF resin added boric acid was improved. However, boric acid addition into UF resin did not negatively affected on shear strength of rubberwood plywood.
อริสรา หิริโอตัปปะ ปิติพร ฤทธิเรืองเดช* และ ศุมาพร เกษมสำราญ
In this study, Near-Infrared spectroscopy (NIRs) was used as a rapid technique to analyze the total soluble solids (TSS) and total sugar content (TS) of 100 fresh cane juice samples. Prior to NIR and reference analyses, the temperature of samples was controlled at 20°C by water bath. NIR spectra of samples were collected in reflectance mode in a wavelength region of 600-2500 nm using an NIR instrument with a liquid cell. Subsequently, the TSS and TS of samples were analyzed according to the AOAC method. Partial least squares (PLS) regression with a full cross-validation method was applied to develop the calibration model. All of the samples for modelling were split into a calibration set (n = 70) and prediction set (n = 30). The results show that the TSS of the samples are from 7.40 to 21.80°Brix, whereas the TS are from 7.05 to 24.13%. The NIR spectra of cane juice samples are dominated by water absorption bands at 1450 and 1950 nm. It is known that sugars display bands in the wavelength region of 1100-1600 nm and 1700-2300 nm. The PLS calibration models with a high predictive performance are devised for TSS and TS with the residual predictive deviation values of 14.47 and 9.50, respectively.
ศุภรัตน์ ดวนใหญ่* สุชาดา มานอก และ เพชรน้ำผึ้ง รอดโพธิ์
The objectives of this study were to determine the antioxidant activity and the growth inhibition of the microorganisms causing atopic dermatitis (eczema) by various essential oils from 7 natural sources including Ocimum tenuiflorum L. (leaves), Alpinia alangal (Linn.) Swartz. (rhizomes), Cymbopogon nardus (Linn.) Rendle. (leaf sheaths), Citrus hystrix DC. (fruit peels and leaves) and Citrus aurantifolia (Christm) Swing (fruit peels and leaves) The antioxidant tests used were 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method and thiobarbituric reactive substances (TBARs) assay for lipid peroxidation. For antioxidant activity by DPPH assay, the results revealed that the essential oils of Cymbopogon nardus (Linn.) Rendle (leaf sheaths) possessed the highest IC50 of 0.116 ± 0.04 mg/ml, better than that of essential oils from Ocimum tenuiflorum L. (leaves) and Alpinia alangal (Linn.) Swartz. (rhizomes) with IC50 of 0.349 ± 0.91 mg/ml, and 0.418 ± 0.10mg/ml, respectively. For lipid peroxidation by TBARs assay, the results revealed that the essential oil of Cymbopogon nardus (Linn.) Rendle possessed the highest IC50 of 0.537 ± 1.08 mg/ml, better than that of essential oils from Alpinia alangal (Linn.) Swartz. (rhizomes) and Ocimum tenuiflorum L. (leaves) with IC50 of 0.586 ± 0.70mg/ml and 0.724 ± 0.27 mg/ml, respectively. Growth inhibition tests for 3 microorganisms by various essential oil showed that Cymbopogon nardus (Linn.) Rendle. provided the most inhibitory effects for Staphylococcus aureus Staphylococcus epidermidis and Candida albicans with the MIC of 0.98, 1.95 and 0.06 - 0.12 mg/ml, respectively. For the growth inhibition of Trichophyton mentagrophytes, Citrus aurantifolia (Christm) Swing (peels) and. Citrus hystrix DC. (peels) provided most inhibitory effects with the MIC of 0.24-0.49 and 0.49 mg/ml, respectively. The results of this study also revealed the potential utilization of the extracts of native medicinal plants in the growth inhibition of pathogenic microorganisms in order to cure and prevent the atopic dermatitis. For more benefits, Thai medicinal herbs can be commercially promoted for their significant usages.
รัตวรรณ พูดเพราะ* นฤมล ธนานันต์ และจุฬา วิริยะบุบผา
Fruits of elephant apple (Dillenia indica) are edible and also used for treatment of diabetes by action as the inhibitor of carbohydrate hydrolyzing enzyme. In this research, the aqueous extracts from edible parts of fresh and boiled fruits of D. indica were determined the presence of phytochemicals; including total phenolic, flavonoid and condensed tannin contents, evaluated of human pancreatic a-amylase inhibitory activity and studied of the stability of active phytochemicals. The results showed that the boiled fruit extract contained more total phenolic, flavonoid and condensed tannin contents than the fresh fruit extract. In addition, the boiled fruit extract (% inhibition = 100.00 ± 0.00, IC50 = 25.40 ± 2.42mg/ml) had a higher capacity to inhibit the human pancreatic a-amylase than the fresh fruit extract (% inhibition = 98.17 ± 3.96, IC50 = 51.39 ± 2.65 mg/ml). Moreover, the active phytochemicals were stable under dark condition at –20 ºC for 3 months. These results suggested that fruits of D. Indic are suitable to develop as a nutraceuticals for diabetes management.
ขวัญชนก เหมียดนอก สายทอง สมบัติภูธร พิชิต โนนตูม อดิศักดิ์ สุมาลี และ อำภา คนซื่อ*
Ko klan remedy is folklore medicine inherit from Thai ancestor which have been used to healing since the past until now. The drugs have been locally used in an herbal remedy for the relief of muscle pain. Aims of this study were evaluated to total phenolic content and antioxidant activities of aqueous extract from Ko klan Remedy. The antioxidations were tested using by Ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging and 2,2 -azinobis-(3-ethylbenzothiazoline-6-sulphonate) (ABTS+) assay. The ko klan recipe will be consist of 3 formulas. The study showed that 1st formula was higher content of total phenolic compounds which drugs composed with Mallotus repandus: Rhinacanthus nasutus: Elephantopus scaber: Aegle marmelos: 1: 1:1:1 (w:w:w:w). 2nd formula which composes with Mallotus repandus: Rhinacanthus nasutus: Elephantopus scaber: Aegle marmelos; 5:2.5:1.5:1.5 (w:w:w:w) was highest antioxidant activity by ABTS assay (IC50 = 0.002±0.00001 mg/mL). 3rd formula were highest reducing by FRAP assay (29.1053±0.2362 mgTE/gEtx) and free radical scavenging by DPPH assay (IC50 = 0.011±0.00004 mg/mL) which drugs contained with Mallotus repandus: Rhinacanthus nasutus: Elephantopus scabe: Ceasalpinia sappan: Cryptolepis buchanani: Piper interruptum; 2:1:1:2:2:2 (w:w:w:w). Moreover, the results found that the three formulas were antioxidation higher than Ascorbic acid and Trolox as standard substances. Further study, chemical composition(s) and pharmaceutical activity were clarified to develop medicinal plant usage.
ศันสนีย์ อุดมระติ* วิภา สุโรจนเมธากุล สุภัคชนม์ คล่องดี และ นพรัตน์ ชี้ทางดี
The applications of native maltodextrin with dextrose equivalent of 9 (DE9) and amphiphilic esterified maltodextrin DE9 palmitate (DE9_P) with concentration of 0.5-3% (w/w) in salad dressing were investigated in terms of stability and rheological properties. The color of salad dressing containing 0.5% (w/w) of DE9 or DE9_P was similar to control sample (no adding of DE9 or DE9_P). DE9 and DE9_P with concentration of 1.5 and 3% (w/w) induced darker yellow color of salad dressing. There was no change in pH value and viscosity and the small increase of average oil droplets size was observed for all samples during storage. The viscosity and flow behavior index (nemulsion) of salad dressing were increased as DE9 or DE9_P was applied. Salad dressing containing DE9 or DE9_P exhibited Newtonian flow behavior more obviously than control sample. There was no change in nemulsion of all samples throughout storage time of 6 weeks because all salad dressing samples (including control sample) were stable. Hence, the function of DE9_P for emulsion stabilization enhancement was not clearly observed. DE9 and DE9_P may use to adjust the viscosity and the textural characteristics of salad dressing.
ขัตติยะ สระแก้ว อาทิตย์ ฉิ่งสูงเนิน* ปรเมษฐ์ จันทร์เพ็ง และ วราภรณ์ สุทธิสา
The purpose of this research is to develop the multihole atmospheric pressure plasma jet (APPJ) for improving seed germination and growth. In this research, SolidWorks 2016 was used to design gas flow simulation inside the plasma source. The simulated results show that gas velocity at nozzle is uniform. As a result, there are the argon plasma beam come out every hole and no arcing. The APPJ was connected to the x-y-z scanner for controlling the plasma beam passing thoroughly with the seed. The length of the plasma beam is around 1 cm. The argon flow rates of 200 250 300 350 L/h were used to evaluate the optimum condition for stable discharge. It founds that the AC power of 893 W and a frequency of 52 kHz with the argon flow rate of 250 L/h is the suitable condition. The mung bean seed was used to study the effect of plasma treatment. The experimental results show that the treated and untreated seed have different seed growth. The treated seed gives a higher growth rate than the control around 18%. This is due to the effect of oxygen nitrogen and humid radicals in plasma which can increase the surface free energy of seed coat. As a result, the treated seed can absorb higher oxygen and moisture from the environmental.
สุพัตรา วงศ์ศรียา และ นิชาภา เฉตระการ
This study aims to study the orbital period, physical components and simulation of an eclipsing binary EH Cnc. Moreover, a closer look at an existence of the third body in this system for determined the evolution of contact binary system is also examined. The data are collected via observation at the Regional Observatory for the Public, Nakhon Ratchasima provided by National Astronomical Research Institute of Thailand (Public Organization) by using 28-inch refracting telescope (PlaneWave CDK) recorded with Apogee U9000 CCD. Two filters, Blue (B) and Yellow (V) in UVB system are also used. The collected data are used to create the light curve in order to form an (O-C) diagram, which is a time difference between the expected and observed eclipse. It is found that the eclipsing binary EH Cnc has a small residual between the primary and the secondary eclipse. The orbital period of this system is 0.4180267 days. The orbital period decreasing rate is 1.16 x 10-3 sec per year causing by momentum loss due to AML theory. Analysis of the (O-C)2 diagram provides a clue about an existence of the third body in the system located at 0.4332 AU from the center of mass. The light curve is analyzed by using PHOBE 0.31a software. It is revealed that the mass ratio of EH Cnc is 2.85, the inclination is 85.70±0.06 degree and the surface temperatures of the primary and secondary stars are 6,400 and 6,350 Kelvin, respectively. The data suggest that this system consists of F0 type star located on the Main sequence of the Hertzsprung-Russell diagram with a physical simulation structure of deep-contact binary system of W UMa type.
สาครินทร์ หาบุศย์ และ ณัฏฐ์ ดิษเจริญ*
This research aims to analyze coding errors in 43 files database systems for medical records department using data mining techniques. We compare performance of decision tree (C4.5 algorithm) and Naïve Bayes algorithms in analyzing and classifying the errors. In addition, association rules for analyzing ICD-10 coding errors among the data was also generated by the Apriori algorithm. 33,862 records of data used in analysis were collected during October 1st, 2016 to September 30th, 2017. Weka 3.8.1 was used to analyze and generate models. The results, when evaluating the classification efficiency with 10-folds cross validation method, showed that the classification accuracy of the decision tree was 90.16%, and that of the Naïve Bayes algorithm was 89.87%. When analyzing the data using Apriori algorithm, the result showed that the error code found the most was error code B4 which is referred to the outpatient code of the vaccine (Z23.0 -Z27.9) with no code of physical and health examination Z00.0-Z00.9, Z01.0-Z01.9, Z02.0-Z02.9.
The purpose of this study was to construct the model for forecasting quantity of natural rubber imports. The data gathered from the website of Office of Agricultural Economics from January 2011 to July 2019 of 103 values were used and divided into 2 sets. The first set had 96 values from January 2011 to December 2018 for constructing the forecasting models by Box-Jenkins method, Holt’s exponential smoothing method, Brown’s exponential smoothing method, damped trend exponential smoothing method, simple seasonal exponential smoothing method, Winters’ additive exponential smoothing method, Winters’ multiplicative exponential smoothing method, and combined forecasting method. The second set had 7 values from January to July 2019 for comparing the accuracy of the forecasting model via the criterion of the lowest mean absolute percentage error. Research findings indicated that, the most accurate method is the combined forecasting method.
ศิริพร ดวงพรม และ แคทรียา สุทธานุช*
This research aimed to investigate cytotoxic and cosmeceutical effect of Dipterocarpus alatus Roxb. (Yang-na in Thai) bark extract, the influencing on cell viability by using MTT assay and in collagen synthesis of dermal fibroblasts by using a collagen dye test, and potential on wound healing using an in vitro cell migration model.The potential of Yang-na bark extract concentration 100 µg/mL was demonstrated, the increasing of fibroblast cell proliferation and synthesized collagen content as high as 161.04 - 282.57% and 103.69 – 136.81% of control, respectively. Accordantly, wound healing effect of Yang-na extract was manifested in reduction of wound-mimic scratch lesion (width of 59.50 – 71.35% of control) at 48 h after Yang-na treatment. This was found in similar manner as gallic acid at concentration of 5 µg/mL, the standard reference (scratch lesion width of 64.53%of control). The results exhibited the beneficial biological properties of Yang-na bark extract concentration 100 µg/mL in wound healing process with mechanisms related stimulation of cell proliferation and collagen synthesis in dermal fibroblasts. The obtained information will be useful for further research and development for substantial utilization of Yang-na bark extract in medical and aesthetical anti-aging purposes.